Chitin synthase inhibitor 12
Chitin synthase inhibitor 12 is a chitin synthase inhibitor. Chitin synthase inhibitor 12 shows excellent inhibitory activity with an IC50 value of 0.16 mM. Chitin synthase inhibitor 12 also is a broad-spectrum antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 12 can be used for the research of invasive fungal infections (IFIs) [1].
Product Specifications
CAS Number
[2725075-05-6]
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/chitin-synthase-inhibitor-12.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(F)C(Cl)=C1)/C=C/C(N2CCC3(CC2)C4=CC(OC)=CC=C4NC(O3)=O)=O
Molecular Formula
C23H21ClFN3O5
Molecular Weight
473.88
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
SPA17 (Sperm Autoantigenic Protein 17, Sperm Protein 17, SP17, Sp17-1, Sperm Surface Protein Sp17, Cancer/testis Antigen 22, CT22) (MaxLight 550)
SPA17 (Sperm Autoantigenic Protein 17, Sperm Protein 17, SP17, Sp17-1, Sperm Surface Protein Sp17, Cancer/testis Antigen 22, CT22) (MaxLight 550)
PDPK1 (3a Phosphoinositide Dependent Protein Kinase 1, Pyruvate Dehydrogenase Kinase Isoform 1, PDK1, PDPK2, PRO0461) discontinued
PDPK1 (3a Phosphoinositide Dependent Protein Kinase 1, Pyruvate Dehydrogenase Kinase Isoform 1, PDK1, PDPK2, PRO0461) discontinued