Chitin synthase inhibitor 6
Chitin synthase inhibitor 6 (compound 9b) is a potent chitin synthase (CHS) inhibitor with an IC50 value of 0.21 mM. Chitin synthase inhibitor 6 has broad-spectrum antifungal activity against drug-resistant fungi. Chitin synthase inhibitor 6 can be used in the research of fungi infection[1].
Product Specifications
CAS Number
[3033645-29-0]
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/chitin-synthase-inhibitor-6.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(OC)C=C1)/C=C/C(N2CCC3(CC2)C4=CC(OC)=CC=C4NC(O3)=O)=O
Molecular Formula
C24H25N3O6
Molecular Weight
451.47
References & Citations
[1]Xu Y, et, al. Spiro[benzoxazine-piperidin]-one derivatives as chitin synthase inhibitors and antifungal agents: Design, synthesis and biological evaluation. Eur J Med Chem. 2022 Aug 31;243:114723.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
G2035-05C 100 µg
GIRK2 (G-Protein-activated Inward Rectifier Potassium Channel 2, GIRK-2, BIR1, Inward Rectifier K (+) Channel Kir3.2, KATP-2, Potassium Channel, Inwardly Rectifying Subfamily J Member 6, KCNJ6, KATP2, KCNJ7)
Ask
View Details 
MBS6477272-01 0.2 mL
Gab1, Phosphorylated (Tyr659) (GRB2-associated Binder Protein 1, Growth Factor Receptor Bound Protein 2-associated Protein 1, GRB2-associated Binder 1) (APC)
Ask
View Details MBS6477272-02 5x 0.2 mL
Gab1, Phosphorylated (Tyr659) (GRB2-associated Binder Protein 1, Growth Factor Receptor Bound Protein 2-associated Protein 1, GRB2-associated Binder 1) (APC)
Ask
View Details