HCAIX-IN-13
HCAIX-IN-13 (Pt2) is an inhibitor of CAIX (arbonic anhydrase IX) with an IC50 value of 6.57 μM. hCAIX-IN-13 inhibits growth of cancer cells and induces cell apoptosis, it can be used for the research of cancer[1].
Product Specifications
CAS Number
2813334-66-4
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaix-in-13.html
Solubility
10 mM in DMSO
Smiles
O=C(CCCC(NCCC1=CC=C(S(=O)(N)=O)C=C1)=O)NC2=CC3=CC=C[N]4=C3C5=[N]([Pt+2]46[C-]7=C(C8=[N]6C=CC=C8)C=CC=C7)C=CC=C52.FC(F)(S(=O)([O-])=O)F
Molecular Formula
C37H33F3N6O7PtS2
Molecular Weight
989.90
References & Citations
[1]Yang J, et al. NIR phosphorescent cyclometalated platinum (II) complexes with CAIX targeted and nuclear penetration as potent anticancer theragnostic agents. Eur J Med Chem. 2022 Aug 31;243:114702.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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