Antitumor agent-76
Antitumor agent-76 (Compound TP-P1) is an orally active, rapid-release and water-soluble Triptolide (HY-32735) proagent with antitumor activity[1].
Product Specifications
CAS Number
[2787593-12-6]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-76.html
Solubility
10 mM in DMSO
Smiles
O=C1OCC2=C1CC[C@]3([C@]2(C[C@H]4[C@@]5([C@]36O[C@H]6[C@@H]7O[C@@]7([C@H]5OC(COC(CN8CCOCC8)=O)=O)C(C)C)O4)[H])C.Cl
Molecular Formula
C28H36ClNO10
Molecular Weight
582.04
References & Citations
[1]Kang D, et al. Discovery of a novel water-soluble, rapid-release triptolide prodrug with improved drug-like properties and high efficacy in human acute myeloid leukemia. Eur J Med Chem. 2022 Sep 5;243:114694.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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