Tubulin polymerization-IN-35
Product Specifications
UNSPSC Description
Tubulin polymerization-IN-35 is an inhibitor of [1,2]oxazoloisoindoles tubulin polymerization, demonstrates high selectivity against marginal zone lymphoma VL51 cell line[1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-35.html
Solubility
10 mM in DMSO
Smiles
COC1=C(OC)C(OC)=CC(C2=C3CCC4=C(ON=C4CN5CCCC5)C3=CN2CC6=CC=C(OC)C=C6)=C1
Molecular Weight
529.63
References & Citations
[1]Marilia Barreca, et al. Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas, European Journal of Medicinal Chemistry. 2022, 114744, ISSN 0223-5234.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151396/Tubulin-polymerization-IN-35-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151396/
Clinical Information
No Development Reported
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