Tubulin polymerization-IN-35

Tubulin polymerization-IN-35 is an inhibitor of [1,2]oxazoloisoindoles tubulin polymerization, demonstrates high selectivity against marginal zone lymphoma VL51 cell line[1].

Product Specifications

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-polymerization-in-35.html

Solubility

10 mM in DMSO

Smiles

COC1=C(OC)C(OC)=CC(C2=C3CCC4=C(ON=C4CN5CCCC5)C3=CN2CC6=CC=C(OC)C=C6)=C1

Molecular Formula

C31H35N3O5

Molecular Weight

529.63

References & Citations

[1]Marilia Barreca, et al. Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas, European Journal of Medicinal Chemistry. 2022, 114744, ISSN 0223-5234.