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Tubulin polymerization-IN-33

Tubulin polymerization-IN-33 is an inhibitor of [1,2]oxazoloisoindoles tubulin polymerization, exhibits high antiproliferative activity against the NCI panel[1].

Product Specifications

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-polymerization-in-33.html

Solubility

10 mM in DMSO

Smiles

OCC1=NOC2=C1CCC3=C(C4=CC(OC)=C(OC)C(OC)=C4)N(CC5=CC=C(OC)C=C5)C=C23

Molecular Formula

C27H28N2O6

Molecular Weight

476.52

References & Citations

[1]Marilia Barreca, et al. Development of [1,2]oxazoloisoindoles tubulin polymerization inhibitors: Further chemical modifications and potential therapeutic effects against lymphomas, European Journal of Medicinal Chemistry. 2022, 114744, ISSN 0223-5234.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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