DPP-4-IN-2
DPP-4-IN-2 (compound b2) is a potent DPP-4 (dipeptidyl peptidase 4) inhibitor, with an IC50of 79 nM. DPP-4-IN-2 is a structurally analogs of Alogliptin. DPP-4-IN-2 can be used for diabetes research[1].
Product Specifications
CAS Number
2133900-95-3
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dpp-4-in-2.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CC=CC=C1CN(C(N2CCNCC2)=C3)C4=CC=NN4C3=O
Molecular Formula
C18H18N6O
Molecular Weight
334.38
References & Citations
[1]Shen J, et al. Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors. Eur J Med Chem. 2020 Dec 15;208:112850.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DPP-4
Frequently Asked Questions
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