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DPP-4-IN-1

DPP-4-IN-1 (compound d1) is a potent DPP-4 (dipeptidyl peptidase 4) inhibitor, with an IC50of 49 nM. DPP-4-IN-1 is a structurally analogs of Alogliptin (HY-A0023A) . DPP-4-IN-1 can be used for diabetes research[1].

Product Specifications

CAS Number

[2215027-46-4]

UNSPSC

12352005

Target

Dipeptidyl Peptidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/dpp-4-in-1.html

Solubility

10 mM in DMSO

Smiles

ClC1=NC2=CC=NN2C(N3C[C@@H](CCC3)N)=C1CC4=C(C=CC=C4)C#N

Molecular Formula

C19H19ClN6

Molecular Weight

366.85

References & Citations

[1]Shen J, et al. Structural optimization of pyrazolo[1,5-a]pyrimidine derivatives as potent and highly selective DPP-4 inhibitors. Eur J Med Chem. 2020 Dec 15;208:112850.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-151383/DPP-4-IN-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-151383/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

DPP-4

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