SAP2-IN-1
SAP2-IN-1 is a secreted aspartic protease 2 (SAP2) inhibitor and has potent SAP2 inhibitory activity with an IC50 value of 0.92 μM. SAP2-IN-1 also is a virulence factor inhibitor and is inactive in vitro. SAP2-IN-1 can be used for the research of infection[1].
Product Specifications
CAS Number
2512847-37-7
UNSPSC
12352005
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sap2-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(C2=CC=C(/C(C3=O)=C\C4=CC=C(OCC(O)=O)C=C4OCC(O)=O)C(N3CC5=CC=C(C)C=C5)=C2)C=C1
Molecular Formula
C34H29NO7
Molecular Weight
563.60
References & Citations
[1]Chenglan Li, et al. Targeting fungal virulence factor by small molecules: Structure-based discovery of novel secreted aspartic protease 2 (SAP2) inhibitors. Eur J Med Chem. 2020 Sep 1;201:112515.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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