MurA-IN-2
Product Specifications
UNSPSC Description
MurA-IN-2 (compound 37), a chloroacetamide fragment containing a primary aliphatic amine, is a potent MurA inhibitor with an IC50 value of 39 ?μM. MurA-IN-2 has antibacterial activity and inhibits the bacterial cell wall synthesis[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mura-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1CCCC2CCCCC12)CCl
Molecular Weight
229.75
References & Citations
[1]Grabrijan K, et, al. Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead. Eur J Med Chem. 2022 Sep 13; 114752.|[2]Grabrijan K, et, al. Covalent inhibitors of bacterial peptidoglycan biosynthesis enzyme MurA with chloroacetamide warhead. Eur J Med Chem. 2022 Sep 13; 114752.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151373/MurA-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151373/
Clinical Information
No Development Reported
CAS Number
2164447-18-9
Curated Selection
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