SENP2-IN-1
SENP2-IN-1 (compound 77) is a selective SENP2 inhibitor. SENP2-IN-1 shows inhibitory activities with IC50s of 1.3, 0.69 and 22.7 μM for SENP1, SENP2 and SENP5, respectively. SENP2-IN-1 can be used for the research of cancer[1].
Product Specifications
CAS Number
[2986220-46-4]
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/senp2-in-1.html
Purity
98.05
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OCC)CNC1=CC=C2C(C(OCC3=CC=CC=C3)=C(C(NCC4=CC=CC(NC(C5=CC=CS5)=O)=C4)=O)S2)=C1
Molecular Formula
C32H29N3O5S2
Molecular Weight
599.72
References & Citations
[1]Wang Z, et al. Benzothiophene-2-carboxamide derivatives as SENPs inhibitors with selectivity within SENPs family. Eur J Med Chem. 2020 Oct 15;204:112553.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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