SphK2-IN-1
SphK2-IN-1 is a SphK2 inhibitor (IC50: 0.359 μM) . SphK2-IN-1 can be used in the research of cancer, inflammation, neurological and cardiovascular disorders[1].
Product Specifications
CAS Number
2927429-64-7
UNSPSC
12352005
Target
SphK
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/sphk2-in-1.html
Solubility
10 mM in DMSO
Smiles
N=C(N1CCC[C@H]1C2=NC(C3=CC=C(C=C3)CN4C=C(N=N4)C5=CC=C(C=C5)C(F)(F)F)=NO2)N.Cl
Molecular Formula
C23H22ClF3N8O
Molecular Weight
518.92
References & Citations
[1]Vijai Kumar Reddy Tangadanchu, et al. Structure-activity relationship studies and bioactivity evaluation of 1,2,3-triazole containing analogues as a selective sphingosine kinase-2 inhibitors. Eur J Med Chem. 2020 Nov 15;206:112713.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SphK2
Available Sizes
Frequently Asked Questions
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