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Antitumor agent-74

Antitumor agent-74 (compound 13da) is a quinoxalines derivative, an antitumor agent. Antitumor agent-74 exhibits more potent efficacy on tumor inhibition, mixed with regioisomer Antitumor agent-75 (mriBIQ 13da/14da). mriBIQ 13da/14da attests cell cycle at S phase, inhibits DNA synthesis, and induces mithochondrial apoptosis[1].

Product Specifications

CAS Number

2827065-28-9

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-74.html

Solubility

10 mM in DMSO

Smiles

CN1CCN(C2=CC=C3N=C(C4=CC=C(F)C=C4)C(C5=NC6=CC=CC=C6N5)=NC3=C2)CC1

Molecular Formula

C26H23FN6

Molecular Weight

438.50

References & Citations

[1]Vakhid AM, et al. Synthesis of Morpholine-, Piperidine-, and N-Substituted Piperazine-Coupled 2- (Benzimidazol-2-yl) -3-arylquinoxalines as Novel Potent Antitumor Agents. ACS Pharmacol. Transl. Sci. 2022, XXXX, XXX, XXX-XXX.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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