ALK5-IN-27
Product Specifications
UNSPSC Description
ALK5-IN-27 (Compound EX-04) is a potent ALK-5 inhibitor with an IC50 ≤10 nM. ALK5-IN-27 also inhibits ALK-2 (selectivity ALK2/ALK5 ≤10)[1].
Target Antigen
TGF-β Receptor
Type
Reference compound
Related Pathways
TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alk5-in-27.html
Solubility
10 mM in DMSO
Smiles
CN1CCN(CC2=CC(NC3=NC=CC(NC4=C5C=CC=C(C)C5=NN=C4)=N3)=CC=C2)CC1
Molecular Weight
440.54
References & Citations
[1]Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151273/ALK5-IN-27-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151273/
Clinical Information
No Development Reported
CAS Number
2785430-83-1
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