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ALK5-IN-26

ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 with an IC50 value ≤10 nM. ALK5-IN-26 can be used for the research of cancer[1].

Product Specifications

CAS Number

2785430-82-0

UNSPSC

12352005

Target

Anaplastic lymphoma kinase (ALK)

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/alk5-in-26.html

Solubility

10 mM in DMSO

Smiles

CC1=CC=CC2=C(NC3=NC(NC4=CC(CN5CCNCC5)=CC=C4F)=NC=C3)C=NN=C12

Molecular Formula

C24H25FN8

Molecular Weight

444.51

References & Citations

[1]Franz B, et al. ALK-5 INHIBITORS AND USES THEREOF. WO/2022/126133 A1. 2022.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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