ALK5-IN-26
ALK5-IN-26 (EX-22) is an ALK (Activin receptor-like kinase) inhibitor. ALK5-IN-26 inhibits ALK5 with an IC50 value ≤10 nM. ALK5-IN-26 can be used for the research of cancer[1].
Product Specifications
CAS Number
2785430-82-0
UNSPSC
12352005
Target
Anaplastic lymphoma kinase (ALK)
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alk5-in-26.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=CC2=C(NC3=NC(NC4=CC(CN5CCNCC5)=CC=C4F)=NC=C3)C=NN=C12
Molecular Formula
C24H25FN8
Molecular Weight
444.51
References & Citations
[1]Franz B, et al. ALK-5 INHIBITORS AND USES THEREOF. WO/2022/126133 A1. 2022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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