CYP2C9/CYP2C19-IN-1

CYP2C9/CYP2C19-IN-1 (compound 22d) is a potent CYP2C9/CYP2C19 inhibitor, possessing no hepatotoxicity and ames toxicity. CYP2C9/CYP2C19-IN-1 can be used in study of anti-ZIKV[1].

Product Specifications

CAS Number

[3010895-55-0]

UNSPSC

12352005

Target

Cytochrome P450; Virus Protease

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cyp2c9-cyp2c19-in-1.html

Solubility

10 mM in DMSO

Smiles

COC1=C(C(C)(C)C)C=C(N(C(N2)=O)C=CC2=O)C=C1C3=CC4=CC=C(CCS(=O)(O)=O)C=C4C=C3

Molecular Formula

C27H28N2O6S

Molecular Weight

508.59

References & Citations

[1]Ezeh M I, et al. Chemoinformatic Design and Profiling of Derivatives of Dasabuvir, Efavirenz, and Tipranavir as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase and Methyltransferase. ACS Omega, 2022.