HIV-1 protease-IN-7
HIV-1 protease-IN-7 (compound 16) is an orally active HIV-1 protease inhibitor (IC50=3.52 nM, EC50=37 nM) [1].
Product Specifications
CAS Number
[2916441-36-4]
UNSPSC
12352209
Target
HIV Protease
Type
Peptides
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-protease-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C1N[C@@H](CC(C)C)C(N[C@@H](CCC2CCCCC2)C(N[C@H](C(N([C@H](C(N[C@@H](C)C(N[C@H](C(OC)=O)C(C)(C)SCC(N[C@H](C(N[C@H](C(N3CCC[C@@](C(N[C@H]1C(C)C)=O)3C)=O)C(C)C)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CC=CC=C5)C)=O)CC(C)C)=O)=O
Molecular Formula
C68H104N10O12S
Molecular Weight
1285.68
References & Citations
[1]Kusumoto Y, et al. Highly Potent and Oral Macrocyclic Peptides as a HIV-1 Protease Inhibitor: mRNA Display-Derived Hit-to-Lead Optimization. ACS Medicinal Chemistry Letters, 2022.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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