MAO-B-IN-15
MAO-B-IN-15 is a selective MAO-B inhibitor (IC50: 13.5 μM) that forms π-π interaction with Tyr 326 residue. MAO-B-IN-15 can be used in the research of Parkinson’s disease[1].
Product Specifications
CAS Number
[2032436-79-4]
UNSPSC
12352005
Target
Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mao-b-in-15.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(C=C1OC)CCN(C3=CC=C(F)C=C3)C2
Molecular Formula
C17H18FNO2
Molecular Weight
287.33
References & Citations
[1]Makito Yamada, et al. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. https://doi.org/10.1021/acsmedchemlett.2c00228.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAO-A; MAO-B
Curated Selection
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