MAO-B-IN-15

MAO-B-IN-15 is a selective MAO-B inhibitor (IC50: 13.5 μM) that forms π-π interaction with Tyr 326 residue. MAO-B-IN-15 can be used in the research of Parkinson’s disease[1].

Product Specifications

CAS Number

[2032436-79-4]

UNSPSC

12352005

Target

Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mao-b-in-15.html

Solubility

10 mM in DMSO

Smiles

COC1=CC2=C(C=C1OC)CCN(C3=CC=C(F)C=C3)C2

Molecular Formula

C17H18FNO2

Molecular Weight

287.33

References & Citations

[1]Makito Yamada, et al. Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. https://doi.org/10.1021/acsmedchemlett.2c00228.