DHU-Se1
DHU-Se1 is a potent anti-inflammatory agent. DHU-Se1 can stimulate macrophages to release the reactive selenium compound and reduce the expression of cellular inflammatory factors (eg: iNOS and TNF-α) . DHU-Se1 alleviate the process of inflammation by blocking the polarization of macrophages from M0 to M1[1].
Product Specifications
UNSPSC
12352005
Target
NO Synthase; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dhu-se1.html
Solubility
10 mM in DMSO
Smiles
CN(C1=CC=C2C(SC3=C(N2C([Se]C4=CC=CC=C4)=O)C=CC(N(C)C)=C3)=C1)C
Molecular Formula
C23H23N3OSSe
Molecular Weight
468.47
References & Citations
[1]Peng H, et al. HOCl-Activated Reactive Organic Selenium Delivery Platform for Alleviation of Inflammation. Bioconjug Chem. 2022 Aug 26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
INOS
Frequently Asked Questions
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