XO/COX/LOX-IN-1
XO/COX/LOX-IN-1 (compound 7i) is a potent xanthine oxidase/cyclooxygenases/lipoxygenases (XO/COX/LOX) inhibitor. XO/COX/LOX-IN-1 can be used in studies of inflammation, cancer and metabolic diseases[1].
Product Specifications
CAS Number
2831329-35-0
UNSPSC
12352005
Target
COX; Lipoxygenase; Xanthine Oxidase
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/xo-cox-lox-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1=NC2=C(C=CC=C2OCC3=NN=C(COC4=CC=CC5=C4N=C(C=C5)C)S3)C=C1
Molecular Formula
C24H20N4O2S
Molecular Weight
428.51
References & Citations
[1]Zabiulla, et al. In-silico docking, synthesis, structure analysis, DFT calculations, energy frameworks, and pharmacological intervention of [1,3,4]-thiadiazoles analogous as XO inhibitor and on multiple molecular inflammatory targets COX and LOX. Journal of Molecular Structure. 2021 Dec;1253 (1-2) :132272.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC740391-100 1x 100 µL
CD81 / TAPA-1 (1.3.3.22), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680149-500 1x 500 µL
CD106 / VCAM1 (1.4C3), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC402400-100 1x 100 µL
OLIG2 (Marker of Glial Brain Tumors) (OLIG2/2400), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940500-100 1x 100 µL
Progesterone Receptor (PR500), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680775-500 1x 500 µL
Pgp9.5 (UCHL-1) (UCHL1/775), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 