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LasR-IN-2

LasR-IN-2 is a LasR inhibitor that forms H-bonding with TRY-56 residue. LasR-IN-2 can be used in the research of bacterial infection, neutropenia, severe burns and chronic lung disease in cystic fibrosis (CF) [1].

Product Specifications

CAS Number

3033530-61-6

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/lasr-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=CC=C1)COC2=CC=C(C3=NC4=CC(Cl)=CC=C4N3)C=C2

Molecular Formula

C21H16ClN3O2

Molecular Weight

377.82

References & Citations

[1]Rehab H Abd El-Aleam, et al. Design and synthesis of novel benzimidazole derivatives as potential Pseudomonas aeruginosa anti-biofilm agents inhibiting LasR: Evidence from comprehensive molecular dynamics simulation and in vitro investigation. Eur J Med Chem. 2022 Aug 5;241:114629.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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