LasR-IN-2
LasR-IN-2 is a LasR inhibitor that forms H-bonding with TRY-56 residue. LasR-IN-2 can be used in the research of bacterial infection, neutropenia, severe burns and chronic lung disease in cystic fibrosis (CF) [1].
Product Specifications
CAS Number
3033530-61-6
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/lasr-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=CC=C1)COC2=CC=C(C3=NC4=CC(Cl)=CC=C4N3)C=C2
Molecular Formula
C21H16ClN3O2
Molecular Weight
377.82
References & Citations
[1]Rehab H Abd El-Aleam, et al. Design and synthesis of novel benzimidazole derivatives as potential Pseudomonas aeruginosa anti-biofilm agents inhibiting LasR: Evidence from comprehensive molecular dynamics simulation and in vitro investigation. Eur J Med Chem. 2022 Aug 5;241:114629.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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