HER2-IN-12
Product Specifications
UNSPSC Description
HER2-IN-12 is a HER2 inhibitor (IC50: 121 nM). HER2-IN-12 can be used in the research of cancers, such as breast cancer[1].
Target Antigen
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/her2-in-12.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CSC2=NC(CN3CCOCC3)=C(C4=CC=C(Br)C=C4)N21)NN
Molecular Weight
436.33
References & Citations
[1]Mohamed A Sabry, et al. New thiazole-based derivatives as EGFR/HER2 and DHFR inhibitors: Synthesis, molecular modeling simulations and anticancer activity. Eur J Med Chem. 2022 Aug 10;241:114661.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151162/HER2-IN-12-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151162/
Clinical Information
No Development Reported
CAS Number
2820126-51-8
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