AChE-IN-24
Product Specifications
UNSPSC Description
AChE-IN-24 is a potent AChE inhibitor and can penetrate the BBB. AChE-IN-24 has the mighty inhibitory activity to hAChE with an IC50 value of 0.053 μM. AChE-IN-24 can be used for the research of Alzheimer s disease (AD)[1].
Target Antigen
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-24.html
Solubility
10 mM in DMSO
Smiles
O=C(OC)/C=C/C(NC1=CC=CC(OCCCCSC(N2C(C)CCCC2)=S)=C1)=O
Molecular Weight
450.61
References & Citations
[1]Jie Guo, et al. A multi-target directed ligands strategy for the treatment of Alzheimer's disease: Dimethyl fumarate plus Tranilast modified Dithiocarbate as AChE inhibitor and Nrf2 activator. Eur J Med Chem. 2022 Aug 11;242:114630.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151152/AChE-IN-24-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151152/
Clinical Information
No Development Reported
CAS Number
3033542-32-1
Curated Selection
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