α-Glucosidase-IN-19

α-Glucosidase-IN-19 (Compound 6B) is a potent, orally active α-glucosidase inhibitor with an IC50 of 3.63 μM. α-Glucosidase-IN-19 shows anti-diabetic activity[1].

Product Specifications

UNSPSC

12352005

Target

Glycosidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/α-glucosidase-in-19.html

Solubility

10 mM in DMSO

Smiles

CC1=CC=C(C=C1)C2=NC3=C(SC(C2)C4=CC=C(C=C4)/C=C/C(C5=CC=CC=C5)=O)C=CC=C3

Molecular Formula

C31H25NOS

Molecular Weight

459.60

References & Citations

[1]Mehmood R, et al. Synthesis of Novel 2, 3-Dihydro-1, 5-Benzothiazepines as α-Glucosidase Inhibitors: In Vitro, In Vivo, Kinetic, SAR, Molecular Docking, and QSAR Studies. ACS Omega, 2022 Aug 17.