α-Glucosidase-IN-17
α-Glucosidase-IN-17 (Compound 12B) is a potent, orally active α-glucosidase inhibitor with an IC50 of 3.79 μM. α-Glucosidase-IN-17 shows antidiabetic activity[1].
Product Specifications
CAS Number
2820424-84-6
UNSPSC
12352005
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/α-glucosidase-in-17.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(C2CC(C3=CC=C(C=C3)C)=NC4=C(S2)C=CC=C4)=CC=C1OCC5=CC=CC=C5
Molecular Formula
C30H27NO2S
Molecular Weight
465.61
References & Citations
[1]Mehmood R, et al. Synthesis of Novel 2, 3-Dihydro-1, 5-Benzothiazepines as α-Glucosidase Inhibitors: In Vitro, In Vivo, Kinetic, SAR, Molecular Docking, and QSAR Studies. ACS Omega, 2022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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