CBR Agonist-2

CBR Agonist-2 is a CB1 agonist (CB1R; CB1 ligand) with an EC50 and a Ki of 960 nM and 970 nM, respectively. CBR Agonist-2 is a promising tool for investigating the involvement of hCB1R in disorders associated with the endocannabinoid system[1].

Product Specifications

UNSPSC

12352005

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cbr-agonist-2.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CN(C2=CC=CC=C12)CCCCCF)NCC3=CC=CC=C3/N=N/C4=CC=CC=C4

Molecular Formula

C27H27FN4O

Molecular Weight

442.53

References & Citations

[1]Diego A Rodríguez-Soacha, et al. Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CB 1 R) "Cis-On" Agonist. ACS Chem Neurosci.2022 Jul 26. doi: 10.1021/acschemneuro.2c00160.