Neuraminidase-IN-10

Neuraminidase-IN-10 is a potent neuraminidase (NA) inhibitor with anti-influenza activity. Neuraminidase-IN-10 is against H1N1, H5N1, and H5N8 with IC50 values of 2.6 nM, 5.1 nM, and 1.65 nM, respectively[1].

Product Specifications

CAS Number

[2685786-29-0]

UNSPSC

12352005

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/neuraminidase-in-10.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C[C@@H](OC(CC)CC)[C@H](NC(C)=O)[C@@H](NCC2=CC=C(C3=CC=CS3)C=C2OC)C1)O

Molecular Formula

C26H34N2O5S

Molecular Weight

486.62

References & Citations

[1]Han Ju, et al. Iterative Optimization and Structure-Activity Relationship Studies of Oseltamivir Amino Derivatives as Potent and Selective Neuraminidase Inhibitors via Targeting 150-Cavity. J Med Chem. 2022 Aug 8. doi: 10.1021/acs.jmedchem.1c01970.