Fabimycin

Fabimycin is a FabI inhibitor with potent antibacterial activity against gram-negative bacteria. Fabimycin is effective against drug-resistant gram-negative Infections in vivo[1].

Product Specifications

CAS Number

[2651965-71-6]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/fabimycin.html

Solubility

10 mM in DMSO

Smiles

O=C(/C=C/C(C=C1CC[C@@H]2[NH3+])=CN=C1NC2=O)N(C)CC(O3)=C(C)C4=C3C=CC=C4.[Cl-]

Molecular Formula

C23H25ClN4O3

Molecular Weight

440.92

References & Citations

[1]Erica N. Parker, et al. An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections. DOI: 10.1021/acscentsci.2c00598.