Fabimycin
Fabimycin is a FabI inhibitor with potent antibacterial activity against gram-negative bacteria. Fabimycin is effective against drug-resistant gram-negative Infections in vivo[1].
Product Specifications
CAS Number
[2651965-71-6]
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/fabimycin.html
Solubility
10 mM in DMSO
Smiles
O=C(/C=C/C(C=C1CC[C@@H]2[NH3+])=CN=C1NC2=O)N(C)CC(O3)=C(C)C4=C3C=CC=C4.[Cl-]
Molecular Formula
C23H25ClN4O3
Molecular Weight
440.92
References & Citations
[1]Erica N. Parker, et al. An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections. DOI: 10.1021/acscentsci.2c00598.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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