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HCAII-IN-5

HCAII-IN-5 (compound 12h) is a potent and selective hCA II inhibitor with an IC50 value of 4.55 μM[1].

Product Specifications

CAS Number

2816080-16-5

UNSPSC

12352005

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hcaii-in-5.html

Solubility

10 mM in DMSO

Smiles

N#CC(C1C2=CC=CC=C2OCC(C3=O)=CC4=C(O3)C=CC=C4)=C(N)OC(C5=C(O6)C=C(O)C=C5)=C1C6=O

Molecular Formula

C29H18N2O7

Molecular Weight

506.46

References & Citations

[1]Nadia Arif, et al. Synthesis, Biological Evaluation, and In Silico Studies of Novel Coumarin-Based 4H,5H-pyrano[3,2-c]chromenes as Potent β-Glucuronidase and Carbonic Anhydrase Inhibitors. American Chemical Society. 2022

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CA II

Frequently Asked Questions

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