ROS1-IN-1
ROS1-IN-1 (Compound 31) is a potent and selective ROS1 kinase inhibitor with an IC50 of 0.097 μM[1].
Product Specifications
CAS Number
[2883232-34-4]
UNSPSC
12352005
Target
ROS Kinase
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ros1-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1=NC(N(CC2=CC=C(C(Cl)=C2)C#N)C)=NC(NC3=NC=CS3)=C1
Molecular Formula
C17H15ClN6S
Molecular Weight
370.86
References & Citations
[1]Petrović D, et al. Virtual Screening in the Cloud Identifies Potent and Selective ROS1 Kinase Inhibitors. J Chem Inf Model. 2022 Aug 3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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