ROS1-IN-1
Product Specifications
UNSPSC Description
ROS1-IN-1 (Compound 31) is a potent and selective ROS1 kinase inhibitor with an IC50 of 0.097 μM[1].
Target Antigen
ROS Kinase
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ros1-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1=NC(N(CC2=CC=C(C(Cl)=C2)C#N)C)=NC(NC3=NC=CS3)=C1
Molecular Weight
370.86
References & Citations
[1]Petrović D, et al. Virtual Screening in the Cloud Identifies Potent and Selective ROS1 Kinase Inhibitors. J Chem Inf Model. 2022 Aug 3.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150974/ROS1-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150974/
Clinical Information
No Development Reported
CAS Number
2883232-34-4
Curated Selection
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