hCAII-IN-4
Product Specifications
UNSPSC Description
hCAII-IN-4 (Compound 12j) is a potent hCA II inhibitor with an IC50 of 7.78 μM. hCAII-IN-4 also inhibits β-glucuronidase with an IC50 of 773.9 μM[1].
Target Antigen
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hcaii-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C1C2=CC=CC=C2OCC(C3=O)=CC4=C(O3)C=CC=C4)=C(N)OC(C5=C(O6)C=C(O)C=C5)=C1C6=O)OCC
Molecular Weight
553.52
References & Citations
[1]Arif N, et al. Synthesis, Biological Evaluation, and In Silico Studies of Novel Coumarin-Based 4 H, 5 H-pyrano [3, 2-c] chromenes as Potent β-Glucuronidase and Carbonic Anhydrase Inhibitors. ACS Omega, 2022.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150973/hCAII-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150973/
Clinical Information
No Development Reported
CAS Number
2816080-18-7
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