ICy-OH
ICy-OH, an iodinated photosensitizer, is an effective anticancer agent. ICy-OH can be used not only for deep tissue imaging (λex=640 nm, λem=690-740 nm) but also to selectively induce cell death in pancreatic cancer cells via cell pyroptosis pathway[1].
Product Specifications
CAS Number
2863682-80-6
UNSPSC
12352005
Target
Pyroptosis
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/icy-oh.html
Solubility
10 mM in DMSO
Smiles
OC1=CC2=C(C=C1)C=C3CCCC(/C=C/C4=[N+](C)C5=C(C=C(I)C=C5)C4(C)C)=C3O2.[I-]
Molecular Formula
C26H25I2NO2
Molecular Weight
637.29
References & Citations
[1]Bo Peng, et al. NQO-1 Enzyme-Activated NIR Theranostic Agent for Pancreatic Cancer. Anal Chem. 2022 Aug
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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