Antiproliferative agent-11
Product Specifications
UNSPSC Description
Antiproliferative agent-11 (compound 7) is an antiproliferative and selective Ruthenium(II)-Tris-pyrazolylmethane complex. Antiproliferative agent-11 shows antiproliferative activity towards MCF-7, HeLa, 518A2, HCT116 and RD with IC50s of 6, 10, 6.8, 6.7 and 6 μM, respectively. Antiproliferative agent-11 can be used for the research of cancer[1].
Target Antigen
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antiproliferative-agent-11.html
Solubility
10 mM in DMSO
Smiles
[H]c12n3cccn3[Ru+](n4n2ccc4)(Cl)([P](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)([P](OC)(OC)OC)n8n1ccc8.[Cl-]
Molecular Weight
772.56
References & Citations
[1]Cervinka J, et al. Ruthenium(II)-Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis. J Med Chem. 2022 Aug 1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150968/Antiproliferative-agent-11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150968/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
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