NDT-30805
Product Specifications
UNSPSC Description
NDT-30805 is a selective NLRP3 inflammasome inhibitor. NDT-30805 is a triazolopyrimidinone derivative and inhibits IL-1β release in PBMCs with an IC50 of 0.013 μM. NDT-30805 can be used for the research of inflammation and innate immunity[1].
Target Antigen
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ndt-30805.html
Solubility
10 mM in DMSO
Smiles
S=C1C=C(CC2=NC=CC=C2)NC3=NC(NC4=C5CCCC5=CC6=C4CCC6)=NN13
Molecular Weight
414.53
References & Citations
[1]David H, et al. Discovery and Optimization of Triazolopyrimidinone Derivatives as Selective NLRP3 Inflammasome Inhibitors. ACS Medicinal Chemistry Letters. 2022.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150965/NDT-30805-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150965/
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7085057 Inquire
Recombinant Debaryomyces hansenii Lysophospholipase NTE1 (NTE1), partial
Ask
View Details 
MBS9908640-01 48 Well
Mouse Testis-Specific Chromodomain Protein Y 1 (CDY1) ELISA Kit
Ask
View Details 
MBS9908640-02 96 Well
Mouse Testis-Specific Chromodomain Protein Y 1 (CDY1) ELISA Kit
Ask
View Details MBS9908640-03 5x 96 Well
Mouse Testis-Specific Chromodomain Protein Y 1 (CDY1) ELISA Kit
Ask
View Details