RAD51-IN-8
RAD51-IN-8, a new RAD51 binder, is a RAD51-BRCA2 inhibitor that inhibits the RAD51 BRCA2 protein protein interaction. RAD51-IN-8 also is a protein protein interaction (PPI) inhibitor. RAD51-IN-8 has inhibitory activity for H4A4 with an EC50 value of 19 μM[1].
Product Specifications
UNSPSC
12352005
Target
RAD51
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rad51-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C(N/N=C/C1=CC=CN=C1F)CCCOC2=CC=C(Cl)C=C2Cl
Molecular Formula
C16H14Cl2FN3O2
Molecular Weight
370.21
References & Citations
[1]Greta Bagnolini, et al. Identification of RAD51–BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry. ACS Med. Chem. Lett. 2022.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1032652-01 0.02 mg (E-Coli)
Recombinant Mycobacterium bovis Uncharacterized protein Mb1374 (Mb1374)
Ask
View Details 
MBS1032652-02 0.02 mg (Yeast)
Recombinant Mycobacterium bovis Uncharacterized protein Mb1374 (Mb1374)
Ask
View Details 
MBS1032652-03 0.1 mg (E-Coli)
Recombinant Mycobacterium bovis Uncharacterized protein Mb1374 (Mb1374)
Ask
View Details MBS1032652-04 0.1 mg (Yeast)
Recombinant Mycobacterium bovis Uncharacterized protein Mb1374 (Mb1374)
Ask
View Details