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SARS-CoV-2-IN-23

SARS-CoV-2-IN-23 (compound GRL-0617) is a SARS-COV-2 papain-like protease (PLpro) inhibitor with an IC50 value of 2.3 μM[1].

Product Specifications

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-in-23.html

Solubility

10 mM in DMSO

Smiles

CC1=CC=C(C=C1C(C([C@@H](C2=CC=CC3=CC=CC=C32)C)N)=O)N

Molecular Formula

C21H22N2O

Molecular Weight

318.41

References & Citations

[1]Ferreira GM, et al. Inhibitor induced conformational changes in SARS-COV-2 papain-like protease. Sci Rep. 2022 Jul 8;12 (1) :11585.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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