PLP_Snyder530
PLP_Snyder530 is a potent papain-like protease (PLpro) inhibitor with an IC50 value of 6.4 μM. PLP_Snyder530 induces conformational changes in SARS-COV-2 papain-like protease, inhibiting SARS-CoV-2 replication. PLP_Snyder530 can be used for SARS-CoV-2 research[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/plp-snyder530.html
Solubility
10 mM in DMSO
Smiles
C=CC(NC1=CC=C(C(C(C([C@@H](C2=CC=CC3=CC=CC=C32)C)N)=O)=C1)C)=O
Molecular Formula
C24H24N2O2
Molecular Weight
372.46
References & Citations
[1]Ferreira GM, et, al. Inhibitor induced conformational changes in SARS-COV-2 papain-like protease. Sci Rep. 2022 Jul 8;12 (1) :11585.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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