NS1219
NS1219 ((R) -SPD502) is the isomer of NS 1209 HY-15074. NS1209 is a selective AMPA receptor antagonist with neuroprotective activity. NS1209 can be used for the research of stroke, neuropathic pain and epilepsy[1].
Product Specifications
CAS Number
233603-81-1
Product Name Alternative
(R) -SPD502
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ns1219.html
Solubility
10 mM in DMSO
Smiles
OCC[C@@H](C(O)=O)O/N=C1C2=C(NC/1=O)C3=C(CCN(C3)C)C(C4=CC=C(C=C4)S(N(C)C)(=O)=O)=C2
Molecular Formula
C24H28N4O7S
Molecular Weight
516.57
References & Citations
[1]Jan M Keppel Hesselink, et al. NS1209/SPD 502, A Novel Selective AMPA Antagonist for Stroke, Neuropathic Pain or Epilepsy? Drug Development Lessons Learned. Drug Dev Res. 2017 Mar;78 (2) :75-80.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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