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EBOV-GP-IN-1

EBOV-GP-IN-1 (Compound 28) is a potent Ebola entry inhibitor with an IC50 of 0.05 μM against Ebola virus envelope glycoprotein (EBOV-GP) [1].

Product Specifications

CAS Number

[3032283-85-2]

UNSPSC

12352005

Target

Filovirus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ebov-gp-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1N(C[C@@H](O)CN[C@H](C2=CC=C(Cl)C=C2)C)C[C@@]3([H])CCCC[C@@]3([H])C1)NC(C)(C)C

Molecular Formula

C25H40ClN3O2

Molecular Weight

450.06

References & Citations

[1]Han S, et al. Discovery of potent ebola entry inhibitors with (3S,4aS,8aS) -2- (3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold. Eur J Med Chem. 2022 Jul 14;240:114608.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

EBOV

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