EBOV-GP-IN-1
EBOV-GP-IN-1 (Compound 28) is a potent Ebola entry inhibitor with an IC50 of 0.05 μM against Ebola virus envelope glycoprotein (EBOV-GP) [1].
Product Specifications
CAS Number
[3032283-85-2]
UNSPSC
12352005
Target
Filovirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ebov-gp-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(C[C@@H](O)CN[C@H](C2=CC=C(Cl)C=C2)C)C[C@@]3([H])CCCC[C@@]3([H])C1)NC(C)(C)C
Molecular Formula
C25H40ClN3O2
Molecular Weight
450.06
References & Citations
[1]Han S, et al. Discovery of potent ebola entry inhibitors with (3S,4aS,8aS) -2- (3-amino-2-hydroxypropyl) decahydroisoquinoline-3-carboxamide scaffold. Eur J Med Chem. 2022 Jul 14;240:114608.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EBOV
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