FtsZ-IN-4
FtsZ-IN-4 is an orally active FtsZ (filamenting temperature-sensitive mutant Z) inhibitor, exhibits excellent antibacterial activity. FtsZ-IN-4 shows good pharmaceutical properties with low cytotoxicity (CC50 >20 μg/mL) [1].
Product Specifications
CAS Number
2882904-64-3
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ftsz-in-4.html
Solubility
10 mM in DMSO
Smiles
NC(C1=C(C=CC(OCC2=CC(C3=CC=C(C=C3C)Cl)=CC=C2)=C1F)F)=O
Molecular Formula
C21H16ClF2NO2
Molecular Weight
387.81
References & Citations
[1]Deng J, et al. Design, synthesis and biological evaluation of biphenyl-benzamides as potent FtsZ inhibitors. Eur J Med Chem. 2022 Sep 5. 239:114553.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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