ODN D-SL03

ODN D-SL03 is a C class CpG oligonucleotides, can induce stimulate PBMCs to produce high level of IFN-α. ODN D-SL03 can activate human B cells, NK cells and mononuclear cells and up-regulate expression of CD80, CD86 and HLA-DR on the surface of subsets in human PBMCs. ODN D-SL03 also can inhibit the growth of the tumor. ODN D-SL03 sequence: 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'[1].

Product Specifications

CAS Number

[1198621-85-0]

UNSPSC

12352208

Target

IFNAR

Type

Oligonucleotides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/odn-d-sl03.html

Purity

99.82

Solubility

H2O : ≥ 20 mg/mL

Smiles

[DNA,d(P-thio)(T-C-G-C-G-A-A-C-G-T-T-C-G-C-C-G-C-G-T-T-C-G-A-A-C-G-C-G-G)]

Molecular Weight

9345.00

References & Citations

[1]Yang L, et al. CpG oligodeoxynucleotides with double stem-loops show strong immunostimulatory activity. Int Immunopharmacol. 2013 Jan;15 (1) :89-96.