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IRAK4-IN-20

IRAK4-IN-20 (Compound BAY-1834845) is an orally active IRAK4 inhibitor with an IC50 of 3.55 nM. IRAK4-IN-20 can be used for acute respiratory distress syndrome (ARDS) research[1].

Product Specifications

CAS Number

1931994-80-7

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

IRAK

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/irak4-in-20.html

Purity

97.04

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=NC(C(F)(F)F)=CC=C1)NC2=CC3=CN(CCC(C)(O)C)N=C3C=C2C(C)(O)C

Molecular Formula

C22H25F3N4O3

Molecular Weight

450.45

Precautions

H315, H319, H335

References & Citations

[1]Li Q, et al. Oral IRAK4 Inhibitor BAY-1834845 Prevents Acute Respiratory Distress Syndrome. Biomedicine & Pharmacotherapy, 2022: 113459.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

IRAK4

Available Sizes

Frequently Asked Questions

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