IRAK4-IN-20

IRAK4-IN-20 (Compound BAY-1834845) is an orally active IRAK4 inhibitor with an IC50 of 3.55 nM. IRAK4-IN-20 can be used for acute respiratory distress syndrome (ARDS) research[1].

Product Specifications

CAS Number

[1931994-80-7]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

IRAK

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/irak4-in-20.html

Purity

97.04

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=NC(C(F)(F)F)=CC=C1)NC2=CC3=CN(CCC(C)(O)C)N=C3C=C2C(C)(O)C

Molecular Formula

C22H25F3N4O3

Molecular Weight

450.45

Precautions

H315, H319, H335

References & Citations

[1]Li Q, et al. Oral IRAK4 Inhibitor BAY-1834845 Prevents Acute Respiratory Distress Syndrome. Biomedicine & Pharmacotherapy, 2022: 113459.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

IRAK4

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ABC-X3044 1 Vial

Xpress™ Human STK39 Over-expressing Stable Cell Line

Ask

View Details

RC208137L2V 200 µL

JRK (NM_003724) Human Tagged ORF Clone Lentiviral Particle

Ask

View Details

NB600-636AF532 0.1 mL

Rabbit Polyclonal PPAR alpha/NR1C1 Antibody [Alexa Fluor 532]

Ask

View Details

LY418253 100 µg

BCL2A1 (NM_004049) Human Over-expression Lysate

Ask

View Details