IRAK4-IN-20
IRAK4-IN-20 (Compound BAY-1834845) is an orally active IRAK4 inhibitor with an IC50 of 3.55 nM. IRAK4-IN-20 can be used for acute respiratory distress syndrome (ARDS) research[1].
Product Specifications
CAS Number
1931994-80-7
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
IRAK
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/irak4-in-20.html
Purity
97.04
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=NC(C(F)(F)F)=CC=C1)NC2=CC3=CN(CCC(C)(O)C)N=C3C=C2C(C)(O)C
Molecular Formula
C22H25F3N4O3
Molecular Weight
450.45
Precautions
H315, H319, H335
References & Citations
[1]Li Q, et al. Oral IRAK4 Inhibitor BAY-1834845 Prevents Acute Respiratory Distress Syndrome. Biomedicine & Pharmacotherapy, 2022: 113459.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IRAK4
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Melanoma Marker (HMB45 + A103 + T311), CF488A conjugate, 0.1mg/mL
Ubiquitin (Autophagy Marker) (UBB/2122), CF740 conjugate, 0.1mg/mL
