ODN 2007
ODN 2007, a class B CpG ODN (oligodeoxynucleotide), is a Toll-like receptor (TLR) ligand. ODN 2007 can be used as an immunomodulator, vaccine adjuvant, and enhance immune responses in mammals, fish, and humans. ODN 2007 sequence: 5'-TCGTCGTTGTCGTTTTGTCGTT-3'[1][2][3].
Product Specifications
CAS Number
455348-63-7
UNSPSC
12352208
Hazard Statement
H315, H319, H335
Target
Toll-like Receptor (TLR)
Type
Oligonucleotides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/odn-2007.html
Purity
93.51
Solubility
H2O : 20 mg/mL (ultrasonic)
Smiles
[DNA,d(P-thio)(T-C-G-T-C-G-T-T-G-T-C-G-T-T-T-T-G-T-C-G-T-T)]
Molecular Weight
6852.50
Precautions
H315, H319, H335
References & Citations
[1]Tamiru N Alkie, et al. Characterization of Innate Responses Induced by PLGA Encapsulated- and Soluble TLR Ligands In Vitro and In Vivo in Chickens. PLoS One. 2017 Jan 3;12 (1) :e0169154. |[2]Hua Chen, et al. CpG-ODN 2007 protects zebrafish (Danio rerio) against Vibrio vulnificus infection. Aquac Res. 2021; 52: 897-905.|[3]Audesh Bhat, et al. Role of Hsp90 in CpG ODN mediated immunostimulation in avian macrophages. Mol Immunol. 2010 Mar;47 (6) :1337-46.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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