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Pim-1 kinase inhibitor 3

Pim-1 kinase inhibitor 3 (Compound H5) is a potent Pim-1 kinase inhibitor with an IC50 of 35.13 nM[1].

Product Specifications

CAS Number

2801695-39-4

UNSPSC

12352005

Target

Pim

Type

Reference compound

Related Pathways

JAK/STAT Signaling

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pim-1-kinase-inhibitor-3.html

Solubility

10 mM in DMSO

Smiles

C12=CC3=C(C=C2)OC4=C(C=CN=C4)N3CCCCCNCCCCO1

Molecular Formula

C20H25N3O2

Molecular Weight

339.43

References & Citations

[1]Xu J, et al. Design, synthesis, and bioactivity evaluation of macrocyclic benzo[b]pyrido[4,3-e][1,4]oxazine derivatives as novel Pim-1 kinase inhibitors. Bioorg Med Chem Lett. 2022 Sep 15;72:128874.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PIM1

Frequently Asked Questions

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