Pim-1 kinase inhibitor 3
Product Specifications
UNSPSC Description
Pim-1 kinase inhibitor 3 (Compound H5) is a potent Pim-1 kinase inhibitor with an IC50 of 35.13 nM[1].
Target Antigen
Pim
Type
Reference compound
Related Pathways
JAK/STAT Signaling
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pim-1-kinase-inhibitor-3.html
Solubility
10 mM in DMSO
Smiles
C12=CC3=C(C=C2)OC4=C(C=CN=C4)N3CCCCCNCCCCO1
Molecular Weight
339.43
References & Citations
[1]Xu J, et al. Design, synthesis, and bioactivity evaluation of macrocyclic benzo[b]pyrido[4,3-e][1,4]oxazine derivatives as novel Pim-1 kinase inhibitors. Bioorg Med Chem Lett. 2022 Sep 15;72:128874.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150731/Pim-1-kinase-inhibitor-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150731/
Clinical Information
No Development Reported
CAS Number
2801695-39-4
Curated Selection
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