COX-2-IN-29
COX-2-IN-29 (Compound 15b) is a selective and orally active COX-2 inhibitor with an IC50 of 0.005 μM[1].
Product Specifications
CAS Number
3033545-21-7
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cox-2-in-29.html
Solubility
10 mM in DMSO
Smiles
O=[N+]([O-])OCCS(CCC1=C(C)N(C2=CC=C(F)C=C2)C(C3=CC=C(S(=O)(C)=O)C=C3)=C1)=O
Molecular Formula
C22H23FN2O6S2
Molecular Weight
494.56
References & Citations
[1]Saletti M, et al. Novel analgesic/anti-inflammatory agents: 1, 5-Diarylpyrrole nitrooxyethyl sulfides and related compounds as Cyclooxygenase-2 inhibitors containing a nitric oxide donor moiety endowed with vasorelaxant properties. European Journal of Medicinal Chemistry, 2022: 114615.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-1; COX-2
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