RSK2-IN-3

RSK2-IN-3 (Compound 26) is a reversible covalent inhibitor of the RPS6KA3 (RSK2) kinase[1].

Product Specifications

CAS Number

[1627136-54-2]

UNSPSC

12352005

Target

Ribosomal S6 Kinase (RSK)

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/rsk2-in-3.html

Solubility

10 mM in DMSO

Smiles

O=C(NC(C)(C)CO)/C(C#N)=C/C1=CC2=C(NN=C2C3=CC(OC)=C(OC)C(OC)=C3)C=C1

Molecular Formula

C24H26N4O5

Molecular Weight

450.49

References & Citations

[1]Hall A, et al. Discovery and Characterization of a Novel Series of Chloropyrimidines as Covalent Inhibitors of the Kinase MSK1. ACS Med Chem Lett. 2022 Jun 25;13 (7) :1099-1108.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

RSK2

Curated Selection

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